Researchers at the 2015 Genitourinary Cancers Symposium reported no new good findings for medical treatments. Instead, the prognoses of some treatments such as abiraterone acetate plus prednisone only allowed 13% of patients with prostate cancer that had already metastasized to reduce their PSA levels to less than or equal to 0.2 ng/ml within one year.
In another trial of men with prostate cancer and bone metastasis, cabozantinib was tested against prednisone. There was no difference between the two groups. In fact, 42% of those receiving the cabozantinib had a 30% reduction or more of bone lesions compared to 3% in the prednisone group. However, the side effects were too serious for many of them to continue the study.
New BPH Medical Procedure Looks Like a Winner
One new outpatient procedure used for men with benign prostatic hyperplasia (BPH) is the Urolift device, which is a local anesthetic outpatient procedure. It involves no catheter and no sexual dysfunction, yet results in rapid symptom relief.
The enlarged prostate weighs a lot more than a normal prostate. The heavy prostate causes compression on the bladder that then causes the urinary frequency symptoms. In the Urolift procedure, the enlarged prostate is lifted up and out of the way so it can’t cause compression symptoms. This was introduced in 2014 so it may start becoming popular in the next few years.
Injection of botulinum toxin into the prostate and injection of ethanol into the prostate is not a procedure that is getting good reviews so stay clear of it. The same is true of the unproven therapies called Histotripsy, Rezum, and Aquablation. BPH – Those on Supplements Still Fare Best Compared to Medications
Herbs still offer the most promise for BPH. In 2013, Chinese researchers reported that Chinese herbal medicine was superior to Western medication in improving quality of life and reducing prostate volume. Adverse effects from the herbs were the same in number as in the placebo group and less than those receiving Western medicine. However, as usual, they concluded that more studies should be done.
Meanwhile, the trend is that men have markedly increased their use of botanicals and supplements for relief of BPH. Men will continue taking their supplements – and the medical professionals at Columbia University Medical Center in New York will continue to make statements such as this one in the World Journal of Urology: “…the sense that natural agents may lack side effects coupled with ineffective communication between the doctor and patient could result in potential adverse interactions.”
Could result? A lot more things COULD happen with medications and medical procedures. Let’s face reality, docs.
The Importance of PDE5 for Sexual Function and BPH
On the other hand, Lebanese researchers have no qualms about holistic treatment. They are convinced that holistic treatment with a PDE5 (phosphodiesterase) inhibitor might benefit men that have erectile dysfunction and BPH together. Surprisingly, they made a jump in logic to conclude this, as their study used the drug Tadaafil, a commonly prescribed PDE5 inhibitor.
Nevertheless, there are herbs or foods that do have PDE5 inhibitor activity such as FRS 1000, an extract of red onion peel. In studies it unexpectedly improved sexual functioning in the bedroom. It’s loaded with a flavonoid called quercetin, which is thought to be responsible for its activity.
Onions before bed? Give it a try!
From my experience with BPH sufferers over the years prescription drugs rarely work to fix the underlying issue and have a number of unpleasant sexual and mental side effects (similar to the infamous Flomax).
The biggest downside of drugs like Flomax is that they do not improve the health of the prostate at all. They are designed purely to relieve symptoms. The result of taking Flomax therefore is that the prostate will continue to deteriorate over time until it becomes necessary to have invasive treatment.
So if you want to avoid prostate cancer and restore your prostate health, make sure you check the 5 Side Effects of Flomax.
I Wish You Good Health,
Ben
References:
Ma, C.H., et al. Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials. Asian J Androl 2013 Jul; 15(4): 471-82.
Kapoor, Anil. What’s new in prostate cancer research? Highlights of GU-ASCO 2015. Can Urol Assoc J 2015 May-Jun; 9(5-6 Suppl3): S148-S153.
Chung, A. and Woo, H.H. What’s truly minimally invasive in benign prostatic hyperplasia. Curr Opin Urol 2014 Jan; 24(1): 36-41.
Capodice, J.L. and Katz, A.E. What patients take without telling you: Holistic approach for BPH. World J Urol 2008 Sep; 24(4): 378-82.
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